Sunday, December 27, 2009

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STEM CELLS: Stem cell therapy in the laws of life

All of us humans, but also every living being originates and develops from a single cell. It is clear that cell and that their daughters must be intrinsically information and skills needed to replicate and transform, rather specialize in all the different cells and tissues that characterize the adult organism. These are the stem cells, known as "totipotent" non-specialized, sensitive to the aging process, with infinite replicative potential.


cells and then characterized by a high capacity to generate and then to regenerate tissues. But cells with characteristics of autonomy and freedom of action similar to cancer cells. During the growth of the embryo these cells give rise to various organs, moving into position, keeping only readable information relevant to the function that has been predetermined for them, "forget" progressively everything that they do not begin to compete and grow old : turn into somatic cells that characterize the adult organism.

Risulta evidente quindi che la possibilità di utilizzare, controllare e direzionare cellule staminali proprie o di altri individui possa essere una grande opportunità terapeutica nelle malattie degenerative, come in quelle genetiche, ma anche in tutte quelle caratterizzate da morte cellulare come ictus ed infarto. È la nuova frontiera della medicina che dopo aver ottenuto grandi risultati con i farmaci “chimici” e un po’ meno con quelli “biologici”, ha oggi a disposizione la possibilità di coltivare delle cellule che possano riprodurre i meccanismi fisiologici dell’organismo, modulare la risposta immune, riparare i danni tissutali e trasformarsi in tessuti di altri individui evitando il rischio del rigetto.
But to achieve this we must overcome many obstacles. The most effective results could be obtained from cells "totipotent," capable of turning into mean any fabric we want.

To do this we should use embryonic cells, with serious ethical implications of the need to withdraw from a human embryo, especially without having the full ability to control directionality and their development. Our knowledge on the phases of operation, reading, transcription of the genetic cell is in fact still far from a genuine understanding of the steps. The real risk and evidence, as mentioned intrinsic to embryonic stem cells, therefore, is to insert cellule senza adeguato controllo e di stimolare anche la nascita di neoplasie nell’individuo ricevente.

Nell’organismo adulto possiamo però trovare cellule con caratteri di multipotenza chiamate staminali adulte. Possono essere prelevate soprattutto dal cordone ombelicale, dal midollo osseo e dal grasso corporeo. Queste cellule hanno caratteristiche di trasformazione e differenziazione molto minori a quelle embrionali, possono specializzarsi in un numero limitato di tessuti, spesso simili a quelli nelle quali sono state prelevate. Sono anche in parte sensibili ai processi di invecchiamento, ma hanno caratteristiche meno vicine alle cellule tumorali e quindi sono utilizzabili con un rischio maggiormente accettabile. Gli scienziati hanno then decided to turn these adult stem cells by increasing its transforming ability.

This could happen with the manipulation of genes that allowed the regression to a pluripotent ottenedo so genetically reprogrammed adult somatic cell-like embryonic (IPS). In the future it is hoped that the "cell therapy" and especially with adult stem cells could take a prominent place in studies, research and experiments, and in this sense, the legislature and the Italian and European regulations provide for this feasibility. Because medical science can progress it is necessary to maintain a given therapeutic use that has been proven be effective to prevent, in addition to brain drain abroad, including that of patients.

Massimiliano Fanni Canelles

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was 1958 when he started a project of the Ministry of Defence of the United States called ARPA (Advanced Research Projects Agency) in an attempt to counter the technological development of 'Soviet Union. In 1966 ARPANET, the first network, launches its first cry and 1971 can not connect with each other 23 computers. But we must wait until 1982 because the word Internet is born: with the creation of TCP / IP sets the standard that would allow interconnections multiple. The shift, however, has in 1991 when CERN (European Organization for Nuclear Research) announces the birth of the World Wide Web (www). Begin to proliferate and service providers in 1992 are already connected to the network of one million computers, which become 600 million in 2008 with more than 600 million active websites and 120,000 blogs are born every day.

Internet is now the main form of communication, storage, consulting, advertising and information. No one had expected, no one has managed to contain it, nobody can control it. The nature of the Internet, since its inception, is in fact to circumvent any possible obstacle. ARPANET was designed specifically to maintain active communication between the "nodes" in the event of war or nuclear holocaust. The system hardware and software has been set with this function and it remains today. The network of networks, as an autonomous entity, grows, expands, always finds new ways to allow connections and ways to circumvent government filters or commercial purposes.

As a social brain, which already has a number of addresses twenty times higher than the number of existing neurons in our brain, has become the most powerful and revolutionary man-made. After merging with each other Western countries, has extended to developing countries, becoming the largest social phenomenon, cultural and democratic history. In many countries allow freedom of expression and democracy, guarantees to the people around the world to see and know everything, even what you would like to keep hidden.

Today, thanks to the Internet, you can have access to information from anywhere on the planet and get answers in seconds. In just over ten years, mankind has accumulated such a large amount of information to transform the entire network in the universal knowledge: from research and studies made by many on-line American universities encyclopedia Wikipedia that has reached one million items, from newspapers to the minute updated information to the operations held non-stop, from personal blogs to the considerations of each of us.

An immense work, created for free by millions of people. Without any coordination, was achieved something that no plan could ever achieve production company and, most importantly, no funding could support. Internet lends it a significance far beyond the possibility of grants with its use. He questioned everything: the control of information, propaganda policy, freedom of thought and speech, the rules of market economy and based on an outdated and anachronistic GDP and, of course, even the legality of the surveillance systems, which must necessarily change and evolve to prevent the use of criminal network.

But above all, was the only instance in history in which each of us, like bees in a hive, has used time and energy to cooperate rather than compete, in an area in which one can never tell who is at the center and the periphery, especially those who are at the top or at the base of the system.

Massimiliano Fanni Canelles

Wednesday, December 16, 2009

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Amor Vincit Omnia

That is, a study of fussiness

As result of the previous post, to continue study sull'inspiegabile hatred that pervades psychos, journalists, judges, politicians, protestors and balls, and much to worry about the Italian government is doing, I put here a clear example of what would otherwise the right tone to use the political arena, to tone down, keep social calm, spread a culture of love.

We start with Chapters 1 and 2, study well it is Christmas and all are good, and we? We do not want mica ... disgrace?

"The leader of the Members of the PDL, Fabrizio Cicchitto , yesterday said in parliament since 1994, taking place in Italy a" hate campaign "against Silvio Berlusconi . Fortunately, the Prime Minister intervened and suffered from 'San Raffaele hospital , where he was admitted after the shameful and inexcusable attack suffered Sunday evening, said that "love conquers hate." This is demonstrated by, among other things, the hundreds of interventions and members of his center-right in the last 15 years have always been based on common sense and moderation. Here then is a necessarily brief anthology of the best sentences of what might be called the Party of Love.
The bon ton with opponents
"Veltroni is a jerk" (Berlusconi, 03/09/1995). "Veltroni is a miserable" (Berlusconi, 04/04/2000). "Giuliano Amato, the useful idiot who sits at Palazzo Chigi" (Berlusconi, 04/21/2000). "Prodi? A borrowed leaders (Berlusconi, 22/02/1995)." The Bindi and Prodi are like thieves Pisa: argue day and night to steal "(Berlusconi, 09/29/1996)." Prodi is the mask Communists "(Berlusconi, 22/05/2003)." Prodi is a liar dangerous for us all "(Berlusconi, 10/21/2006)." Before the election I was able to meet only twice on television, my opponent, and with only two and a half minutes to answer the questions of the journalist and the bullshit that said Prodi. "(Berlusconi at the school of political education of Forza Italy, July 2, 2007)." With Prodi at Palazzo Chigi is right to say it rains Government thief "(Berlusconi, 04/10/2008)." The center? insane, miserable at the barrel of the gas "(Berlusconi, 04/04/2000)." Mr. Schulz, I know that in Italy there is a producer who is assembling a film about Nazi concentration camps. Suggest the for the role of Kapo (inaugurating the Italian Presidency of the European Union and responding to a question from the Social Democratic leader, German Martin Schulz, on conflict of interest, July 2, 2003). "I am in politics because the good prevail over evil . If the left would go to the government, the outcome would be this: misery, terror and death. As with the communist governments everywhere (Berlusconi, 17/01/2005).

Respect for voters
"She has a beautiful face bitch!" (Mrs. Anna Galli Rimini, who complained, 24 / 7 / 2003). "I do not think voters are stupid enough to rely on People like D'Alema and Fassino, who has a moral complicity with those who did the most serious crimes such as Comrade Pol Pot "(Berlusconi, 14 December 2005). "I have too much esteem for the intelligence of Italians to think that there are around so many balls that are permitted to vote by their lack of interest" (Berlusconi's speech in front of the Confcommercio 04/04/2006). "Our three" I ": English, Internet, business. Those of the Olive: insult, insult and insult "(27/05/2004). "


The following lessons can be found here (at your own risk).
Image taken from 'r pisanaccio !